蔡高峰，男，1992年出生，浙江诸暨人，博士研究生，硕士研究生导师，3044am永利集团3044noc校聘教授。2023年毕业于南京农业大学临床中兽医方向，现为中国畜牧兽医学会中兽医学分会会员，江西省微量元素与健康研究会理事，江西省农业农村厅科技特派员。主要研究方向为中药成分作为免疫调控物质，增强肠道黏膜免疫应答，改善肠道微生物菌群结构和促进肠道干细胞分化、潘氏细胞抗菌肽分泌的机制研究，以及中药提取物作为饲料添加剂在防治细菌性腹泻中的“替抗”研究。此外，通过整合纳米材料学与中药多糖免疫活性进行疫苗佐剂设计与开发、保护性免疫应答机制研究，重点对口服黏膜佐剂递送系统进行了深入优化和研究，并取得了一系列的重要进展。现主持国家自然科学基金青年项目1项、江西省自然科学基金青年项目1项、江西省职业早期青年科技人才培养项目1项，省级创新创业项目1项、校教改项目1项，并参与国家自然科学基金2项。近5年先后发表SCI学术论文20余篇，其中第一作者SCI收录6篇，作文核心1篇。
E-mail: cgf19920617@163.com
教育经历（从大学本科开始，按时间倒排序）：
[1] 2019-09至2023-06，南京农业大学，临床兽医学，博士
[2] 2014-09至2017-06，3044am永利集团3044noc，预防兽医学，硕士
[3] 2010-09至2014-06，3044am永利集团3044noc，动物医学，学士
工作经历（科研与学术工作经历，包括国外访学，按时间倒排序）：
2023.7-至今，3044am永利集团3044noc，3044am永利集团3044noc，讲师（校聘教授）
代表性研究成果和学术奖励情况：
[1] Cai, G., Wu, C., Zhu, T., Peng, S., Xu, S., Hu, Y., Liu, Z., Yang, Y., Wang, D. Structure of a Pueraria root polysaccharide and its immunoregulatory activity on T and B lymphocytes, macrophages, and immunosuppressive mice[J]. International Journal of Biological Macromolecules, 2023, 230: 123386. (一作，中科院1区，Top，IF= 8.2)
[2] Cai, G., Wu, C., Mao, N., Song, Z., Yu, L., Zhu, T., Peng, S., Yang, Y., Liu, Z., & Wang, D. Isolation, purification and characterization of Pueraria lobata polysaccharide and its effects on intestinal function in cyclophosphamide-treated mice[J]. International Journal of Biological Macromolecules, 2022, 218: 356-367. (一作，中科院1区，Top，IF= 8.2)
[3] Cai, G., Yang, Y., Gu, P., Li, K., Adelijiang, W., Zhu, T., Liu, Z., & Wang, D. The secretion of sIgA and dendritic cells activation in the intestinal of cyclophosphamide-induced immunosuppressed mice are regulated by Alhagi honey polysaccharides[J]. Phytomedicine, 2022, 103: 154232. (一作，中科院1区，Top，IF= 7.9)
[4] Cai, G., Wu, Y., Wusiman, A., Gu, P., Mao, N., Xu, S., Zhu, T., Feng, Z., Liu, Z., & Wang, D. Alhagi honey polysaccharides attenuate intestinal injury and immune suppression in cyclophosphamide-induced mice[J]. Food & Function, 2021, 12(15): 6863–6877. (一作，中科院1区，Top，IF= 6.317)
[5] Cai, G., Wusiman, A., Gu, P., Mao, N., Xu, S., Zhu, T., He, J., Liu, Z., & Wang, D. Supplementation of Alhagi honey polysaccharides contributes to the improvement of the intestinal immunity regulating the structure of intestinal flora in mice[J]. Food & Function, 2021, 12(20): 9693–9707. (一作，中科院1区，Top，IF= 6.317)
[6] Cai, G., Mao, N., Gu, P., Zhu, T., He, J., Peng, S., Yang, Y., Liu, Z., Hu, Y., Wang, D. Effects of Alhagi Honey Polysaccharides as Feed Supplement on Intestine Function and Microbiome, Immune Function, and Growth Performance in Chicken[J]. International Journal of Molecular Sciences, 2022, 23(22): 14332. (一作，中科院2区，Top，IF= 6.208)
[7] 蔡高峰，毛宁宁，朱天宇，贺瑾，朱少武，薛瑞，雷商商，刘振广，胡元亮，王德云，刺糖多糖对鸡免疫新城疫疫苗后免疫功能的调节作用[J]. 畜牧与兽医, 2023, 55(02): 129-134. (一作，中文核心期刊)
[8] Wusiman, A., He, J., Cai, G., Zhu, T., Bo, R., Liu, Z., Hu, Y., & Wang, D. Alhagi honey polysaccharides encapsulated into PLGA nanoparticle-based pickering emulsion as a novel adjuvant to induce strong and long-lasting immune responses[J]. International Journal of Biological Macromolecules, 2022, 202: 130–140. (中科院1区，Top，IF= 8.025)
[9] Gu, P., Cai, G., Yang, Y., Hu, Y., Liu, J., & Wang, D. Polyethylenimine-coated PLGA nanoparticles containing Angelica sinensis polysaccharide promote dendritic cells activation and associated molecular mechanisms[J]. International Journal of Biological Macromolecules, 2022, 207: 559–569. (中科院1区，Top，IF= 8.025)
[10] Gu, P., Zhang, Y., Cai, G., Liu, Z., Hu, Y., Liu, J., & Wang, D. Administration Routes of Polyethylenimine-Coated PLGA Nanoparticles Encapsulating Angelica Sinensis Polysaccharide Vaccine Delivery System Affect Immune Responses[J]. Molecular pharmaceutics, 2021, 18(6): 2274–2284. (中科院2区，IF= 5.364)
[11] Gu, P., Wusiman, A., Zhang, Y., Cai, G., Xu, S., Zhu, S., Liu, Z., Hu, Y., Liu, J., & Wang, D. Polyethylenimine-coated PLGA nanoparticles-encapsulated Angelica sinensis polysaccharide as an adjuvant for H9N2 vaccine to improve immune responses in chickens compared to Alum and oil-based adjuvants[J]. Veterinary microbiology, 2020, 251: 108894. (中科院1区，Top，IF= 3.293)
[12] Shuwen Xu; Zhiyong Wu; Gaofeng Cai; Yue Zhang; Song Peng; Lina Jiao; Zhenguang Liu; Yang Yang; Deyun Wang. Astragalus polysaccharides combined with simvastatin as an immunostimulant enhances the immune adjuvanticity of oil-in-water emulsion and immune responses in mice[J]. Vaccine. 2023, 41(10): 1684-1693. (中科院3区，IF= 4.169)
[13] Zhang, Yue; Zhu, Tianyu; Xu, Shuwen; Gu, Pengfei; Cai, Gaofeng; Peng, Song; Liu, Zhenguang; Yang, Yang; Hu, Yuanliang; Liu, Jiaguo; Wang, Deyun. Cationic nanoparticles-stabilized vaccine delivery system for the H9N2 vaccine to promote the immune response in chickens. Molecular Pharmaceutics[J]. 2023, 20(3): 1613-1623. (中科院2区，IF= 5.364)
[14] Peng W, Jiang C, Cai G, Liu L, Guo X, Gao X, Li G, Zheng Z, Liu P, Liu P. Preparation of polyclonal antibody against thrombospondin 2 recombinant protein and its functional verification in pulmonary hypertension syndrome in broilers[J]. International Journal of Biological Macromolecules, 2024, 274: 133284. (中科院2区，Top，IF= 7.7)
[15] Yang Y, Lv L, Shi S, Cai G, Yu L, Xu S, Zhu T, Su X, Mao N, Zhang Y, Peng S, He J, Liu Z, Wang D. Polysaccharide from walnut green husk alleviates liver inflammation and gluconeogenesis dysfunction by altering gut microbiota in ochratoxin A-induced mice[J]. Carbohydr Polym, 2023, 322:121362.(中科院1区，Top，IF= 10.7)
[16] Qi Q, Li Y, Ding M, Huang C, Omar SM, Shi Y, Liu P, Cai G, Zheng Z, Guo X, Gao X. Wogonin Inhibits Apoptosis and Necroptosis Induced by Nephropathogenic Infectious Bronchitis Virus in Chicken Renal Tubular Epithelial Cells[J]. International Journal of Molecular Sciences, 2024, 25(15):8194.(中科院3区，IF=4.9)
[17] Chen Y, Feng C, Huang C, Shi Y, Omar SM, Zhang B, Cai G, Liu P, Guo X, Gao X. Preparation of polyclonal antibodies to chicken P62 protein and its application in nephropathogenic infectious bronchitis virus-infected chickens[J]. International Journal of Biological Macromolecules, 2024, 271:132515. (中科院2区，Top，IF= 7.7)
[18] Zeng Y, Shi Y, Chen Y, Zhong S, Omar SM, Liu P, Zhuang Y, Cai G, Guo X, Gao X. Preparation of polyclonal antibody to CHOP protein and its application in heat stress of chickens[J]. International Journal of Biological Macromolecules, 2025, 286:138362. (中科院2区，Top，IF= 7.7)
[19] He J, Zhu T, Mao N, Cai G, Gu P, Song Z, Lu X, Yang Y, Wang D. Cistanche deserticola polysaccharide-functionalized dendritic fibrous nano-silica as oral vaccine adjuvant delivery enhancing both the mucosal and systemic immunity[J]. International Journal of Biological Macromolecules, 2024, 262:129982. (中科院2区，Top，IF= 7.7)
[20] Liu Z, Tang R, Qi Q, Lin S, Liu P, Cai G, Zheng Z, Guo X, Gao X. Naringenin alleviates heat stress-induced liver injury in Ningdu yellow chickens by decreasing RIPK3 and PDC binding[J]. JOURNAL OF NUTRITIONAL BIOCHEMISTRY. 2025, 140:109894.(中科院2区，IF= 4.8)
[21] Peng W, Wan G, Cheng S, Li G, Liu L, Chen J, Liu P, Guo X, Gao X, Cai G, Zheng Z, Liu P. Potential role of TRAF2 in pulmonary hypertension in broiler chickens and preparation and specificity analysis of its polyclonal antibody[J]. International Journal of Biological Macromolecules, 2025, 295:139741.(中科院2区，Top，IF= 7.7)
主持或参加科研项目及人才计划项目情况（按时间倒排序）：
[1] 国家自然科学基金委员会，青年科学基金项目（C类）[原青年科学基金项目]，32402938，葛根多糖调控仔猪肠道潘氏细胞生成溶菌酶预防ETEC感染的机制研究，2025-01-01至2027-12-31，30万元，在研，主持；
[2] 江西省科技计划项目，自然（青年）科学基金，20242BAB20314，葛根多糖-树枝状介孔二氧化硅增强PEDV口服疫苗黏膜免疫效果及其作用机制研究，2024-06-01至2027-05-31，10万元，在研，主持；
[3] 江西省科技计划项目，职业早期青年科技人才培养项目，20244BCE52047，基于肠道微生物研究葛根多糖调控仔猪肠道抗菌肽分泌的作用机制，2024-12-17至2029-12-31，20万元，在研，主持；
[4] 3044am永利集团3044noc人才引进启动项目，30万，在研，主持；
[5] 国家自然科学基金委员会，地区项目，32460850，瘤胃微生物与宿主互作介导葛根素促进肉羊肌内脂肪沉积的机理，2025-01-01至2028-12-31，39万元，在研，参与；
[6] 国家自然科学基金委员会, 面上项目, 32072905, 中药多糖Pickering乳液的佐剂活性及其作用机理的研究, 2021-01-01 至 2024-12-31, 58万元, 在研, 参与。
